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The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).
Gene Name: | gamma-aminobutyric acid (GABA) A receptor, theta |
Family/Subfamily: | Ion Channel , GABA A receptor |
Synonyms: | GABRQ, GABA(A) receptor subunit theta, GABA-A receptor theta subunit, THETA, GABA(A) receptor, theta |
Target Sequences: | NM_018558 |
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