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Anti-GABRA4 Antibody (C-Terminus) LS-C43096

Note: This antibody replaces LS-C23745

Ordering

Wt. Vol. Conc. Price
- 100 µl - $520
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GABRA4 Antibodies

Anti-GABRA4 Antibody (aa349-361) IHC-plus™ LS-B3611
Goat Polyclonal to Human GABRA4
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-GABRA4 Antibody LS-C413661
Rabbit Polyclonal to Human GABRA4
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Rat GABRA4
Rat, Human, Mouse, Bovine
Western blot
Unconjugated

Details

Rat GABRA4
Rabbit
Rat, Human, Mouse, Bovine (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

GABRA4 antibody was raised against synthetic peptide corresponding to the C-Terminal region of the alpha 4 subunit of rat GABA A receptor coupled to KLH. ( C-TERMINAL ).
C-Terminus
The alpha 4 subunit of rat gamma-aminobutyric acid A (GABAA ) receptor. GABAA receptors are GABA gated chloride channels, which are important mediators of neuronal inhibition in the mammalian central nervous system. Activation of the GABAA site results in increased intracellular chloride concentration and hyperpolarization of the cell. GABAA receptors are pentameric structures assembled from a family of distinct subunits. At least fourteen distinct subunits have been identified, which show distinct patterns of temporal and spatial expression. GABAA receptors may be modulated by several drug types including benzodiazepines and barbiturates, and by phosphorylation by protein kinase C (PKC) and protein kinase A (PKA).
Western Blot: LS-C43096 detects a band of approximately 64kD in rat brain lysates.

Packaging

10 mM HEPES, pH 7.5, 0.09% sodium azide, 0.01% BSA, 50% glycerol.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About GABRA4

P48169 NM_000809 NP_000800.2

GABRA4 Antibody, GABA A receptor alpha 4 Antibody, GABA(A) receptor, alpha 4 Antibody

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABA-A receptor subtype. GABA-A receptors are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABA-A receptor is a multimeric subunit complex.

Requested From: United States
Date Requested: 12/4/2016

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