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Anti-GABBR2 / GABA B Receptor 2 Antibody (phospho-Ser783) LS-C61869

Note: This antibody replaces LS-C49094, LS-C42622

Ordering

Wt. Vol. Conc. Price
- 100 µl - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GABBR2 / GABA B Receptor 2 Antibodies

Anti-GABBR2 / GABA B Receptor 2 Antibody (aa42-54) LS-C40599
Rabbit Polyclonal (IgG) to Human GABBR2 / GABA B Receptor 2
Human, Rat
Western blot, ELISA
Unconjugated
Anti-GABBR2 / GABA B Receptor 2 Antibody (aa861-912, clone S81-2) LS-C209507
Mouse Monoclonal [clone S81-2] (IgG1) to Rat GABBR2 / GABA B Receptor 2
Rat, Human, Mouse
IHC, ICC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Rat GABBR2 / GABA B Receptor 2
Rat, Human, Mouse, Bovine, Chicken, Xenopus
Immunofluorescence, Western blot
Unconjugated

Details

Rat GABBR2 / GABA B Receptor 2
Rabbit
Rat, Human, Mouse, Bovine, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Immunofluorescence (1:500)
  • Western blot (1:1000)

Specificity and Use

GABBR2 / GABA B Receptor 2 antibody was raised against phosphopeptide corresponding to amino acid residues surrounding the phosphoSer783 of GABAB R2.
pSer783
Specific for ~102k GABAB R2 phosphorylated at Ser783. Immunolabeling of the GABAB R2 band is completely blocked by lambda-phosphatase treatment

Packaging

50 uL of 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
Long term: -20°C; Short term: -20°C
For research use only.

About GABBR2 / GABA B Receptor 2

O75899 NM_005458 NP_005449.5

GABBR2 Antibody, G protein-coupled receptor 51 Antibody, GABA(B2) Antibody, GABA-B receptor 2 Antibody, Gaba-b receptor r2 Antibody, GABA-BR2 Antibody, Gabab-receptor subunit 2 Antibody, GABA(B)R2 Antibody, GABA-B receptor, R2 subunit Antibody, GABA-B-R2 Antibody, GABAB receptor-2 Antibody, GPRC3B Antibody, Gb2 Antibody, HRIHFB2099 Antibody, G-protein coupled receptor 51 Antibody, GPR51 Antibody, HG20 Antibody, GABA B Receptor 2 Antibody, GABA-B2 Antibody, GABAB2 Antibody, GABABR2 Antibody, Gbr2 Antibody

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.

Western blot

Western blot
Western blot of rat synaptic membrane showing specific immunolabeling of the ~102 k GABAB R2 protein phosphorylated at Ser783 (control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda phosphatase). The blot
 

Requested From: United States
Date Requested: 12/3/2016

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