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Anti-GAB2 Antibody (aa285-676) LS-C7000

Ordering

Wt. Vol. Conc. Price
200 µg - - $515
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Rabbit Polyclonal (IgG) to Human GAB2
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

Details

Human GAB2
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein A purified

Applications

Western blot, Immunoprecipitation

Specificity and Use

GAB2 antibody was raised against gST fusion-protein corresponding to residues 285-676 of human Gab2.
aa285-676
Recognizes human Gab2, Mr 95kD, as well as non-specific bands at 190kD and 105kD at higher antibody concentrations. Species cross-reactivity: mouse and rat.
Suitable for use in Western Blot and Immunoprecipitation. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: 5 ug immunoprecipitated Gab2 from 500 ug of HeLa RIPA lysate. Western Blot Analysis.

Packaging

0.07 M Tris-glycine, pH 7.4, 0.105 M sodium chloride, 0.035% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GAB2

Q9UQC2 NM_012296 NP_036428.1

GAB2 Antibody, GRB2-associated binder 2 Antibody, KIAA0571 Antibody, Pp100 Antibody

Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

Requested From: United States
Date Requested: 9/30/2016

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