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Anti-FZD8 / Frizzled 8 Antibody (Extracellular Domain) LS-C6923


Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml Unavailable
500 µg - - Unavailable

Most Popular FZD8 / Frizzled 8 Antibodies

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IHC - Paraffin
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Anti-FZD8 / Frizzled 8 Antibody LS-C6922
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Anti-FZD8 / Frizzled 8 Antibody (Biotin) LS-C6924
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Anti-FZD8 / Frizzled 8 Antibody LS-C150196
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IHC, Western blot, ELISA

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2a) to Mouse FZD8 / Frizzled 8
Western blot, ELISA


Mouse FZD8 / Frizzled 8
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Protein G purified


  • Western blot (1 - 2 µg/ml)

Specificity and Use

FZD8 / Frizzled 8 antibody was raised against nS0-derived rmFrizzled-8 extracellular domain (CRD).
Extracellular Domain
Recognizes mouse Frizzled-8. In Direct ELISAs, shows approximately 15% cross-reactivity with rmFrizzled-6 and no cross-reactivity with rmFrizzled-1, -2, -3, -4, or -7.
Suitable for use in Western Blot and Direct ELISA. Western Blot: Use at 1-2 ug/ml. Using a colorimetric detection system, the detection limit for rmFrizzled-8 is ~25 ng/lane under reducing conditions. Direct ELISA: Use at 0.5-1.0 ug/ml. The detection limit is ~5 ng/well.


PBS, pH 7.2, 5% trehalose, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About FZD8 / Frizzled 8

Q9H461 NM_031866 NP_114072.1

FZD8 Antibody, Frizzled family receptor 8 Antibody, Frizzled homolog 8 Antibody, FZ-8 Antibody, Fz8 Antibody, Frizzled 8 Antibody, Frizzled-8 Antibody, HFZ8 Antibody

Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.

Requested From: 
Date Requested: 4/23/2017

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