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Anti-FZD7 / Frizzled 7 Antibody (aa33-185) LS-C6915

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Wt. Vol. Conc. Price
100 µg - - $650
Inquire for larger quantities

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Goat Polyclonal (IgG) to Mouse FZD7 / Frizzled 7
Mouse
IHC, Western blot, ELISA
Unconjugated

Details

Mouse FZD7 / Frizzled 7
Goat
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified

Applications

IHC (1.7 - 15 µg/ml), Western blot (0.1 - 0.2 µg/ml), ELISA (0.5 - 1 µg/ml)

Specificity and Use

FZD7 / Frizzled 7 antibody was raised against nS0-derived rmFrizzled-7, amino acids 33-185.
aa33-185
Recognizes mouse Frizzled-7 extracellular Cysteine-Rich Domain (CRD). Approximately 15% cross-reactivity with rmFrizzled-1, 5% cross-reactivity with rmFrizzled-3 and rmFrizzled-6 and less than 2% cross-reactivity with rmFrizzled-4.
Direct ELISA, Western blot, Immunohistochemistry. Direct ELISA: 0.5-1 ug/ml. Western blot: 0.1-0.2 ug/ml with the appropriate secondary reagents to detect mouse Frizzled-6. The detection limit for rmFrizzled-7 is approximately 1 ng/lane under non-reducing and reducing conditions. Immunohistochemistry: 1.7-15 ug/ml.

Packaging

PBS, pH 7.2, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About FZD7 / Frizzled 7

O75084 NM_003507 NP_003498.1

FZD7 Antibody, Frizzled family receptor 7 Antibody, Frizzled homolog 7 Antibody, Frizzled 7 Antibody, Frizzled-7 Antibody, FzE3 Antibody, Fz-7 Antibody, HFz7 Antibody

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.

Requested From: United States
Date Requested: 9/29/2016

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