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Anti-FZD6 / Frizzled 6 Antibody (N-Terminus) IHC-plus™ LS-A4481

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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Rabbit Polyclonal to Human FZD6 / Frizzled 6
Human
IHC - Paraffin
Unconjugated

Details

Human FZD6 / Frizzled 6
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey, Bovine, Horse (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (14 µg/ml)

Specificity and Use

FZD6 / Frizzled 6 antibody was raised against synthetic 17 amino acid peptide from N-terminal extracellular domain of human Frizzled-6. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Horse (94%); Elephant, Pig, Opossum (88%); Panda, Bat, Rabbit (82%).
LS-E28969 - Liquid - 50 µg - $145.00
N-Terminus
Human Frizzled-6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MTMR10 (47%).

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (1)

1
Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma. Bengochea A, de Souza MM, Lefranois L, Le Roux E, Galy O, Chemin I, Kim M, Wands JR, Trepo C, Hainaut P, Scoazec JY, Vitvitski L, Merle P. British journal of cancer. 2008 99:143-50. (IHC-P; Human) [Full Text Article] [PubMed:18577996] [PMC:PMC2453022]

About FZD6 / Frizzled 6

O60353 NM_003506 NP_003497.2

FZD6 Antibody, Frizzled family receptor 6 Antibody, FZ-6 Antibody, HFZ6 Antibody, Frizzled 6 Antibody, Frizzled-6 Antibody, Frizzled homolog 6 Antibody, FZ6 Antibody, NDNC10 Antibody

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.

Immunohistochemistry

Immunohistochemistry
Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A4481 dilution 14 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A4481 dilution 14 ug/ml.

Requested From: United States
Date Requested: 9/29/2016

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