LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-FRS2 Antibody (phospho-Tyr436) LS-C150138

Ordering

Wt. Vol. Conc. Price
100 µg - 0.2 mg/ml $345
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular FRS2 Antibodies

Anti-FRS2 Antibody (aa121-449) LS-C36377
Sheep Polyclonal (IgG) to Human FRS2
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Anti-FRS2 Antibody LS-C146976
Rabbit Polyclonal to Human FRS2
Human, Mouse, Rat
Western blot
Unconjugated
Western blot Image
Anti-FRS2 Antibody (phospho-Tyr436) LS-C150138
Rabbit Polyclonal (IgG) to Human FRS2
Human, Mouse, Rat
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human FRS2
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human FRS2
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1 µg/ml)

Specificity and Use

FRS2 antibody was raised against phosphopeptide containing human FRS2 Y436 site.
pTyr436
Detects human, mouse, and rat FRS2 isoforms when phosphorylated at Y436.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Reconstitute at 0.2 mg/mL in sterile PBS
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About FRS2

Q8WU20 NM_006654 NP_006645.3

FRS2 Antibody, FGFR substrate 2 Antibody, FRS2A Antibody, FGFR signalling adaptor Antibody, FGFR-signaling adaptor SNT Antibody, FRS2alpha Antibody, SNT-1 Antibody, SNT1 Antibody, SNT Antibody

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Western blot

Western blot
Detection of Human and Rat PhosphoFRS2 (Y436) by Western Blot. Western blot shows lysates of MCF- 7 human breast cancer cell line untreated (-) or treated (+) with 100 uM pervanadate (PV) for 10 minutes and PC-12 rat adrenal pheochromocytoma cell line untreated or treated with 100 ng/ml Recombinant Rat beta-NGF for 10 minutes. PVDF membrane was probed with 1 ug/ml of Human/Mouse/Rat PhosphoFRS2 (Y436) Antigen Affinity-purified Polyclonal Antibody, followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody. Bands were detected for Phospho-FRS2 (Y436) at approximately 70-90 kD (as indicated). This experiment was conducted under reducing conditions.
 

Requested From: United States
Date Requested: 12/2/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number