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FOXO3 / FOXO3A
forkhead box O3
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
| Gene Name: | forkhead box O3 |
| Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
| Synonyms: | FOXO3, AF6q21, AF6q21 protein, Forkhead box O3, Forkhead box O3A, FOXO3A, FKHRL1P2, Forkhead box protein O3, FOXO2, FKHRL1 |
| Target Sequences: | NM_001455 NP_001446.1 O43524 |
Publications (1)
1
Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis. Kumar V, Kumar V, Chaudhary AK, Coulter DW, McGuire T, Mahato RI. Molecular therapy. Nucleic acids. 2018 September;12:490-503. [Full Text Article]
[PubMed:30195786]
[PMC:PMC6070673]
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FOXO3 / FOXO3A Mouse anti-Human Monoclonal (3C2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FOXO3 / FOXO3A Goat anti-Human Polyclonal (aa661-673) Antibody
Chicken, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (pThr24/Thr32) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$485
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
FOXO3 / FOXO3A Mouse anti-Human Monoclonal (2H2) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FOXO3 / FOXO3A Mouse anti-Human Monoclonal (4F2) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$440
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DNA Binding
12 x 8-Well Microstrips
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$694
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FOXO3 / FOXO3A Mouse anti-Human Monoclonal (2C5) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (pSer253) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$489
FOXO3 / FOXO3A Mouse anti-Human Monoclonal (4E8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, IHC, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (pSer253) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (pSer253) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
![FOXO3 / FOXO3A Antibody - Immunoperoxidase of monoclonal antibody to FOXO3A on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1.5 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/foxo3-foxo3a-antibody-clone-1d2-ls-c133203/50759_5009941.jpg)
FOXO3 / FOXO3A Mouse anti-Human Monoclonal (1D2) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
![FOXO3 / FOXO3A Antibody - Immunoperoxidase of monoclonal antibody to FOXO3A on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 1.5 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/foxo3-foxo3a-antibody-clone-2c4-ls-c133204/50762_5009942.jpg)
FOXO3 / FOXO3A Mouse anti-Human Monoclonal (2C4) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
FOXO3 / FOXO3A Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (aa224-253) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (aa224-253) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
FOXO3 / FOXO3A Rabbit anti-Human Polyclonal (aa224-253) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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