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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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FOXO1 / FKHR Antibody (phospho‑Ser329) LS‑C177977
FKHR antibody LS-C177977 is an unconjugated rabbit polyclonal antibody to FKHR (FOXO1) from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C177977-100
100 µl
Unavailable

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Product Description

FKHR antibody LS-C177977 is an unconjugated rabbit polyclonal antibody to FKHR (FOXO1) from human, mouse and rat. Validated for IHC and WB.
About FOXO1 / FKHR
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Q12778 NM_002015 NP_002006.2

FOXO1 Antibody, FKHR Antibody, Forkhead in rhabdomyosarcoma Antibody, FOXO1A Antibody, FKH1 Antibody, Forkhead box protein O1 Antibody, Forkhead box protein O1A Antibody, Forkhead box O1 Antibody, Forkhead box o1a Antibody, Forkhead domain protein fkhr Antibody


Specifications

Target
Human FOXO1 / FKHR
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
FOXO1 / FKHR antibody was raised against synthetic phosphopeptide around pSer329 of human FOXO1 / FKHR
Epitope
pSer329
Specificity
Human FOXO1 / FKHR
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.
Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.

Immunohistochemistry

IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.
Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.

Immunohistochemistry

IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.
Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.

Immunohistochemistry

IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of p-FOXO1A (S329) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.
Western blot of p-FOXO1A (S329) pAb in extracts from HeLa cells treated with Serum 20% 15'.


Requested From: 
Date Requested: 6/20/2018

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