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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FOXO1 / FKHR Antibody (clone 3A10) LS‑C104950
FKHR antibody LS-C104950 is an unconjugated mouse monoclonal antibody to human FKHR (FOXO1). Validated for WB.
Catalog
Size
Price
LS-C104950-100
100 µg
Unavailable

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Product Description

FKHR antibody LS-C104950 is an unconjugated mouse monoclonal antibody to human FKHR (FOXO1). Validated for WB.
About FOXO1 / FKHR
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Q12778 NM_002015 NP_002006.2

FOXO1 Antibody, FKHR Antibody, Forkhead in rhabdomyosarcoma Antibody, FOXO1A Antibody, FKH1 Antibody, Forkhead box protein O1 Antibody, Forkhead box protein O1A Antibody, Forkhead box O1 Antibody, Forkhead box o1a Antibody, Forkhead domain protein fkhr Antibody


Specifications

Target
Human FOXO1 / FKHR
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,l Monoclonal [3A10]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • Western blot
Failed Applications
  • IHC - Paraffin
Immunogen
FOXO1 / FKHR antibody was raised against fOXO1A (NP_002006, 452 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Usage
Western Blot (Cell lysate) - positive control SW-13.
Presentation
PBS, pH 7.4
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.
FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.

Western blot

FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.
FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.

Western blot

FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.
FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.

Western blot

FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.
FOXO1A monoclonal antibody (M12), clone 3A10 Western blot of FOXO1A expression in SW-13.


Requested From: 
Date Requested: 6/19/2018

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