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Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Gene Name: | forkhead box H1 |
Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
Synonyms: | FOXH1, Fast-2, FAST2, FAST-1, FAST1, Forkhead box H1, Forkhead box protein H1, HFAST-1 |
Target Sequences: | NM_003923 NP_003914.1 O75593 |
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