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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FOXE2 / FOXE1 Antibody (aa361‑373) IHC‑plus™ LS‑B2492 Best Seller
Note: This antibody replaces LS-C54856
FOXE1 antibody LS-B2492 is an unconjugated goat polyclonal antibody to human FOXE1 (FOXE2). Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B2492-50
50 µg (0.5 mg/ml)
$425

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Product Description

FOXE1 antibody LS-B2492 is an unconjugated goat polyclonal antibody to human FOXE1 (FOXE2). Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
About FOXE2 / FOXE1
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. O00358 NM_004473 NP_004464.2

FOXE1 Antibody, FKHL15 Antibody, Forkhead related protein 15 Antibody, Forkhead box e1 Antibody, Forkhead box E2 Antibody, Forkhead box protein E2 Antibody, FOXE2 Antibody, HNF-3/fork head-like protein 5 Antibody, TITF2 Antibody, TTF-2 Antibody, Thyroid transcription factor 2 Antibody, Forkhead box protein E1 Antibody, HFKH4 Antibody, HFKL5 Antibody


Specifications

Target
Human FOXE2 / FOXE1
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bat, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:8000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
FOXE2 / FOXE1 antibody was raised against synthetic peptide C-AYPGGIDRFVSAM from the C-terminus of human FOXE1 (NP_004464.2). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Marmoset, Elephant, Bat, Rabbit (92%); Mouse, Rat, Panda, Bovine, Pig (85%).
Blocking Peptide
LS-E25565 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B2492. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa361-373
Specificity
Human FOXE1.
Usage
Immunohistochemistry: LS-B2492 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2492 was determined to be 2.5 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Images

Immunohistochemistry

Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.
Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.

Immunohistochemistry

Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.
Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.

Immunohistochemistry

Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.
Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.

Immunohistochemistry

Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.
Anti-FOXE1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2492 concentration 5 ug/ml.

Requested From: United States
Date Requested: 9/19/2018

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