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Anti-FOXC1 Antibody (aa541-553) IHC-plus™ LS-B2996
Note: This antibody replaces LS-C54851, LS-C66329Most Popular FOXC1 Antibodies
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Details
| Human FOXC1 | |
| Goat | |
| Human, Monkey, Mouse, Xenopus, Zebrafish (tested or 100% immunogen sequence identity) | |
| Polyclonal | |
| Unconjugated | |
| Immunoaffinity purified | |
| Unmodified |
Applications
- IHC
- IHC - Paraffin (3.75 µg/ml)
- Western blot (0.5 - 1.5 µg/ml)
- ELISA (1:32000)
Specificity and Use
| FOXC1 antibody was raised against synthetic peptide RTSGAFVYDCSKF from the C-terminus of human FOXC1 (NP_001444.2). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Elephant, Opossum, Xenopus, Stickleback, Pufferfish, Zebrafish (100%); Salmon (92%). | ||
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| aa541-553 | ||
| Human FOXC1. | ||
| Immunohistochemistry: LS-B2996 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2996 was determined to be 3.75 ug/ml. |
Packaging
| Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide | |
| Store at -20°C. Avoid freeze-thaw cycles. | |
| For research use only. |
About FOXC1
Q12948
NM_001453
NP_001444.2
FOXC1 Antibody, Forkhead-like 7 Antibody, FREAC3 Antibody, FKHL7 Antibody, Forkhead-related activator 3 Antibody, Forkhead-related protein FKHL7 Antibody, IGDA Antibody, IHG1 Antibody, IRID1 Antibody, Forkhead box protein C1 Antibody, Mesenchyme fork head protein 1 Antibody, Myeloid factor-delta Antibody, ARA Antibody, Forkhead box C1 Antibody, FREAC-3 Antibody, RIEG3 Antibody
Forkhead box C1 (FOXC1) belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of FOXC1 has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in FOXC1 cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
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Requested From:
Date Requested: 4/21/2018
Date Requested: 4/21/2018
