Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human FOLR1 / Folate Receptor Alpha
IHC - Paraffin, Western blot, ELISA
Goat Polyclonal (IgG) to Bovine FOLR1 / Folate Receptor Alpha
Western blot, Immunoprecipitation, ELISA
Bovine FOLR1 / Folate Receptor Alpha
Bovine (tested or 100% immunogen sequence identity)
Ion exchange chromatography
Specificity and Use
Folate binding protein from bovine milk.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Folate Binding Protein [bovine milk].
Suitable for use in ELISA, Western Blot, Immunoprecipitation and Conjugation. ELISA: 1:10000 to 1:40000; Sandwich ELISA using 1 ug of bovine folate binding protein, rabbit anti-goat IgG-HRP, ABTS substrate, 30min., RT.
PBS, pH 7.2, 0.01% sodium azide, 40% glycerol.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.