Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone Bu10] (IgM) to Human Follicular Dendritic Cells
IHC - Frozen, Flow Cytometry
Human Follicular Dendritic Cells
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [Bu10]
Ion exchange chromatography
IHC - Frozen (1:10 - 1:50)
Specificity and Use
Recognizes a molecule that is expressed on human follicular dendritic cells (FDCs). Follicular dendritic cells are found in the germinal centers of lymphoid organs. The cells have narrow cytoplasmic processes that interdigitate between densely populated areas of B lymphocytes in lymph node follicles and in the spleen.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.