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FN1 / Fibronectin
fibronectin 1
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
| Gene Name: | fibronectin 1 |
| Synonyms: | FN1, CIG, Cold-insoluble globulin, Fibronectin 1, FINC, LETS, GFND, ED-B, Fibronectin, FN, FNZ, GFND2, Migration-stimulating factor, MSF |
| Target Sequences: | NM_002026 NP_002017.1 P02751 |
Publications (4)
1
Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes. Xinlei Li, Ruju Chen, Sherri Kemper, David R Brigstock. Frontiers in cell and developmental biology. 2021 Mar;9:640667. [Full Text Article]
[PubMed:33816490]
[PMC:PMC8012540]
2
Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart. Árpád Kovács , Melissa Herwig , Heidi Budde , Simin Delalat , Detmar Kolijn , Beáta Bódi, Roua Hassoun , Melina Tangos , Saltanat Zhazykbayeva , Ágnes Balogh, Dániel Czuriga, Sophie Van Linthout, Carsten Tschöpe, Naranjan S Dhalla, Andreas Mügge , Attila Tóth , Zoltán Papp , Judit Barta, Nazha Hamdani. Antioxidants. 2021 Jun;10:964. [Full Text Article]
[PubMed:34208541]
[PMC:PMC8234177]
3
Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats. Edwin K Jackson, Zaichuan Mi, Delbert G Gillespie, Dongmei Cheng, Stevan P Tofovic. Journal of the American Heart Association. 2021 March;10:e020088. [Full Text Article]
[PubMed:33682436]
[PMC:PMC8174220]
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FN1 / Fibronectin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$515
FN1 / Fibronectin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$515
FN1 / Fibronectin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
FN1 / Fibronectin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
1 mg/$572
FN1 / Fibronectin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
FN1 / Fibronectin Mouse anti-Human Monoclonal (aa1965-2176) (2F4) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
FN1 / Fibronectin Sheep anti-Horse Polyclonal Antibody
Horse
Unconjugated
1 ml/$290
Sandwich
96-Well Strip Plate
Rat
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
E. coli
His, N-Terminal
14.8 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$585
Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$719
Sandwich
96-Well Microplate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
FN1 / Fibronectin Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Bovine, Rat, Human, Monkey
ELISA, IHC, IP, WB
Biotin Conjugated
100 µg/$559
Sandwich
96-Well Strip Plate
Rat
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
FN1 / Fibronectin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Biotin Conjugated
100 µg/$878
FN1 / Fibronectin Mouse anti-Human Monoclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$930
FN1 / Fibronectin Mouse anti-Human Monoclonal (B476) Antibody
Human
IHC, IHC-Fr
Unconjugated
0.5 ml/$328
FN1 / Fibronectin Mouse anti-Human Monoclonal (2F4) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
FN1 / Fibronectin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
50 µg/$460
FN1 / Fibronectin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (568) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
FN1 / Fibronectin Mouse anti-Human Monoclonal (HFN7.1) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
Sandwich
96-Well Strip Plate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
Sandwich CLIA
96-Well Strip Plate
Human
0.27 - 200 ng/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
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