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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FMR1 / FMRP Antibody (clone 3B4) LS‑C173787
FMRP antibody LS-C173787 is an unconjugated mouse monoclonal antibody to human FMRP (FMR1). Validated for Flow, IF, IHC and WB.
Catalog
Size
Price
LS-C173787-100
100 µl (0.98 mg/ml)
Unavailable

Popular FMR1 / FMRP Products

Antibody
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
IHC of paraffin-embedded human brain tissues, showing cytoplasmic localization with DAB staining using FMR1 mouse monoclonal antibody.
Species: Human
Applications: IHC, Immunofluorescence, Western blot, ELISA
Anti-FMR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3953 concentration 2.5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Hamster, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-FMR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3970 concentration 2.5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-FMR1 / FMRP antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10188 concentration 10 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA

Product Description

FMRP antibody LS-C173787 is an unconjugated mouse monoclonal antibody to human FMRP (FMR1). Validated for Flow, IF, IHC and WB.
About FMR1 / FMRP
Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Q06787 NM_002024 NP_002015.1

FMR1 Antibody, FMRP Antibody, POF Antibody, Protein FMR-1 Antibody, Premature ovarian failure 1 Antibody, Fragile X mental retardation 1 Antibody, FRAXA Antibody, POF1 Antibody


Specifications

Target
Human FMR1 / FMRP
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [3B4]
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:150)
  • Immunofluorescence (1:100)
  • Western blot (1:500)
  • Flow Cytometry (1:100)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
FMR1 / FMRP antibody was raised against human recombinant protein fragment corresponding to amino acids FMR1(NP_002015) produced in E. coli.
Specificity
Human FMR1 / FMRP
Presentation
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.

Immunofluorescence

Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.
Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.

Flow Cytometry

Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).
Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.

Immunofluorescence

Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.
Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.

Flow Cytometry

Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).
Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.

Immunofluorescence

Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.
Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.

Flow Cytometry

Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).
Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-FMR1 mouse monoclonal antibody.

Immunofluorescence

Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.
Anti-FMR1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.

Flow Cytometry

Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).
Flow cytometry of Jurkat cells, using anti-FMR1 antibody (Red), compared to a nonspecific negative control antibody (Blue).


Requested From: 
Date Requested: 6/17/2018

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