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Anti-FMR1 / FMRP Antibody (clone 2D4) LS-C197237

Ordering

Wt. Vol. Conc. Price
100 µg - - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular FMR1 / FMRP Antibodies

Anti-FMR1 / FMRP Antibody (aa594-607) IHC-plus™ LS-B3953
Goat Polyclonal to Human FMR1 / FMRP
Human, Monkey, Mouse, Rat, Bat, Hamster, Pig, Rabbit
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-FMR1 / FMRP Antibody (aa116-130) IHC-plus™ LS-B3970
Goat Polyclonal to Human FMR1 / FMRP
Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Pig, Rabbit
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-FMR1 / FMRP Antibody (C-Terminus) IHC-plus™ LS-B10188
Rabbit Polyclonal (IgG) to Human FMR1 / FMRP
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2D4] (IgG1,k) to Human FMR1 / FMRP
Human
Western blot, ELISA, RNA interference
Unconjugated

Details

Human FMR1 / FMRP
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [2D4]
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot
  • ELISA
  • RNA interference

Specificity and Use

FMR1 / FMRP antibody was raised against fMR1 (NP_002015, aa121-220 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Human FMR1 / FMRP
RNAi Knockdown: Antibody validated. Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Transfected lysate, Recombinant protein.

Packaging

PBS, pH 7.2
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
For research use only.

About FMR1 / FMRP

Q06787 NM_002024 NP_002015.1

FMR1 Antibody, FMRP Antibody, POF Antibody, Protein FMR-1 Antibody, Premature ovarian failure 1 Antibody, Fragile X mental retardation 1 Antibody, FRAXA Antibody, POF1 Antibody

Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm.

Western blot

Western blot
Western Blot analysis of FMR1 expression in transfected 293T cell line by FMR1 monoclonal antibody (M01), clone 2D4.Lane 1: FMR1 transfected lysate(34.1 KDa).Lane 2: Non-transfected lysate.

Western blot

Western blot
FMR1 monoclonal antibody (M01), clone 2D4 Western Blot analysis of FMR1 expression in HepG2.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged FMR1 is approximately 0.1 ng/ml as a capture antibody.

RNA interference

RNA interference
Western blot analysis of FMR1 over-expressed 293 cell line, cotransfected with FMR1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with FMR1 monoclonal antibody (M01), clone 2D4 . GAPDH ( 36.1 kDa ) used as specificity and loading control.

Requested From: United States
Date Requested: 12/7/2016

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