Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1G2] (IgG2a) to Foot-and-Mouth Disease Virus FMDV Non-Structural Protein 3a
Foot-and-Mouth Disease Virus
Foot-and-Mouth Disease Virus FMDV Non-Structural Protein 3a
Foot-and-Mouth Disease Virus (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [1G2]
Specificity and Use
Recombinant FMDV non structural protein 3a.
Recognizes the 3a non-structural protein of Foot-and-mouth disease virus (FMDV). Foot-and-mouth disease virus is a nonenveloped icosahedral Aphthovirus that contains single-stranded RNA. Foot-and-mouth disease is a highly contagious and sometimes fatal disease of cattle, pigs and other cloven-hoofed animals. The disease is characterized by high fever and blisters inside the mouth and on the feet. Although it doesn't have a high mortality rate, the disease has debilitating effects, including weight loss and decrease in milk production, resulting in detrimental economic ramifications. The virus is spread through direct contact. The non-structural proteins are necessary for viral replication and as such mutations in this area are probably less well tolerated than in the rest of the genome. Non-structural proteins have been targeted as possible diagnostic targets to distinguish between infected and vaccinated animals.
PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.