Human FLT3LG / Flt3 Ligand

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Purified

Unmodified

Recombinant human Flt3-Ligand.

Recognizes the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I transmembrane glycoprotein which regulates the proliferation of early hematopoietic cells. Flt3L exists in both a membrane-bound and proteolytically cleaved soluble isoform, both of which are biologically active, and initiates cell proliferation/ differentiation signalling in co-operation with other colony stimulating factors (CSFs) and interleukins, by binding to and activating the tyrosine kinase receptor Flt3 (FLT3R), expressed highly by hematopoietic progenitor cells and stem cells.

• Western blot (0.1 - 0.2 µg/ml)
• ELISA (0.5 µg/ml)

ELISA: May be used in an indirect ELISA system or as a capture antibody in a sandwich ELISA for human Flt3L .

PBS

0.1 ml Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.

Before reconstitution store at 4°C. After reconstitution store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P49771 NCBI: NM_001459 NP_001450.2