Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
FKBP4 / FKBP52 antibody was raised against synthetic peptide corresponding to the residues of human FKBP52.
Detects an ~52 kD protein representing FKBP52 in HeLa cell lysate. Also detects FKBP52 in whole tissue extracts from rat kidney and rat and mouse testes. Heavy chain migrates close to FKBP52 on SDS-PAGE.
Immunoprecipitation: 5 ug with 10-20 ul Protein A beads.
PBS, 50% glycerol, 0.09% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
FKBP4 / FKBP52 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506.
Anti-FKBP52 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7445 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Prostate tissue was histologically stained with antibodies specific for FKBP52. The strongest staining for FKBP52 is in ductal epithelial cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.
FKBP52 (Hi52C), MCF-7 cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.
FKBP52 (Hi52C), Cell lines. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From: United States
Date Requested: 12/11/2016