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Anti-FKBP38 / FKBP8 Antibody (aa326-375) LS-C80950

Catalog Size Price
LS-C80950-50 50 µg Unavailable

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39 FKBP38 / FKBP8 Antibodies

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100% Guaranteed
Rabbit Polyclonal (IgG) to Human FKBP38 / FKBP8
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Goat, Guinea pig, Horse, Pig, Xenopus, Zebrafish
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human FKBP38 / FKBP8
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Goat, Guinea pig, Horse, Pig, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, HRP, FITC.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

FKBP38 / FKBP8 antibody was raised against synthetic peptide located between aa326-375 of human FKBP8 (Q14318, NP_036313). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Mouse, Rat, Goat, Elephant, Panda, Dog, Bovine, Bat, Horse, Pig, Guinea pig, Zebra finch, Xenopus, Salmon, Stickleback, Zebrafish (100%); Opossum (92%).
LS-E17048 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C80950. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa326-375
Human FKBP8 / FKBP38
ELISA titer using peptide based assay: 1:1562500. Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.

Packaging

Lyophilized from PBS with 2% sucrose
50 µl Distilled Water.
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About FKBP38 / FKBP8

Q14318 NM_012181 NP_036313.3

FKBP8 Antibody, 38 kDa FKBP Antibody, 38 kDa FK506-binding protein Antibody, FKBP-8 Antibody, FK506-binding protein 8 Antibody, FKBP38 Antibody, HFKBP38 Antibody, FKBP-38 Antibody, Rotamase Antibody, FK506 binding protein 8, 38kDa Antibody, FK506-binding protein 8 (38kD) Antibody, FKBPr38 Antibody, PPIase FKBP8 Antibody

Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Western blot

Western blot
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 12/14/2017

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