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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FKBP38 / FKBP8 Antibody (aa199‑226) LS‑C166168
FKBP8 antibody LS-C166168 is an unconjugated rabbit polyclonal antibody to human FKBP8 (FKBP38). Validated for WB.
Catalog
Size
Price
LS-C166168-400
400 µl
Unavailable

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Antibody
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Western blot of recombinant FKBP38 / FKBP8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation

Product Description

FKBP8 antibody LS-C166168 is an unconjugated rabbit polyclonal antibody to human FKBP8 (FKBP38). Validated for WB.
About FKBP38 / FKBP8
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. Q14318 NM_012181 NP_036313.3

FKBP8 Antibody, 38 kDa FKBP Antibody, 38 kDa FK506-binding protein Antibody, FKBP-8 Antibody, FK506-binding protein 8 Antibody, FKBP38 Antibody, HFKBP38 Antibody, FKBP-38 Antibody, Rotamase Antibody, FK506 binding protein 8, 38kDa Antibody, FK506-binding protein 8 (38kD) Antibody, FKBPr38 Antibody, PPIase FKBP8 Antibody


Specifications

Target
Human FKBP38 / FKBP8
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E8070 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C166168. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa199-226
Specificity
This FKBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the Central region of human FKBP8.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).
With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).

Western blot

FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).
FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).

Western blot

With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).
With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).

Western blot

FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).
FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).

Western blot

With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).
With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).

Western blot

FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).
FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).

Western blot

With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).
With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 (1:1000, 4 degrees C overnight ) and horseradish peroxidase-conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagent and XAR film (Kodak).

Western blot

FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).
FKBP8 Antibody western blot of CEM cell line lysates (35 ug/lane). The FKBP8 antibody detected the FKBP8 protein (arrow).


Requested From: 
Date Requested: 6/24/2018

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