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Anti-FKBP38 / FKBP8 Antibody (aa199-226, Biotin) LS-C207032

Catalog Size Price
LS-C207032-200 200 µl Unavailable

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58 FKBP38 / FKBP8 Antibodies

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Western blot of recombinant FKBP38 / FKBP8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-FKBP38 / FKBP8 Antibody (aa110-329, Biotin) LS-C688371
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human FKBP38 / FKBP8
Human
Western blot, ELISA (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human FKBP38 / FKBP8
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Biotin. Also available Unconjugated or conjugated with AP, APC, FITC, HRP, PE.
Protein A purified
Unmodified

Applications

  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)

Specificity and Use

aa199-226
This FKBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the Central region of human FKBP8.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, no preservatives added
Short term: store at 4°C. Long term: aliquot and store -20°C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.
For research use only.

About FKBP38 / FKBP8

Q14318 NM_012181 NP_036313.3

FKBP8 Antibody, 38 kDa FKBP Antibody, 38 kDa FK506-binding protein Antibody, FKBP-8 Antibody, FK506-binding protein 8 Antibody, FKBP38 Antibody, HFKBP38 Antibody, FKBP-38 Antibody, Rotamase Antibody, FK506 binding protein 8, 38kDa Antibody, FK506-binding protein 8 (38kD) Antibody, FKBPr38 Antibody, PPIase FKBP8 Antibody

Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Requested From: 
Date Requested: 5/21/2018

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