Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
FKBP1A Antibody, 12 kDa FKBP Antibody, 12 kDa FK506-binding protein Antibody, Calstabin-1 Antibody, FK506 binding protein12 Antibody, Fk506-binding protein Antibody, FKBP12C Antibody, FK506-binding protein 12 Antibody, FKBP-1A Antibody, Immunophilin FKBP12 Antibody, FK506-binding protein 1 Antibody, FKBP1 Antibody, FKBP12-Exip3 Antibody, PKC12 Antibody, PKCI2 Antibody, PPIase FKBP1A Antibody, Protein kinase C inhibitor 2 Antibody, Rotamase Antibody, PPIase Antibody, FK506-binding protein 1A Antibody, FKBP-12 Antibody
FKBP1A / FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FKBP12 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of FKBP12 (arrow) using rabbit polyclonal FKBP12 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FKBP12 gene (Lane 2) (Origene Technologies).