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Anti-Fibrinogen Antibody IHC-plus™ LS-B2573

Note: This antibody replaces LS-C27205


Wt. Vol. Conc. Price
- 50 µl 5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C56206 FITC Conjugated
LS-C56207 HRP Conjugated

Most Popular Fibrinogen Antibodies

Anti-Fibrinogen Antibody (clone 27C8) LS-C52057
Mouse Monoclonal [clone 27C8] (IgG2a) to Human Fibrinogen
Western blot, ELISA
Anti-Fibrinogen Antibody LS-C109177
Rabbit Polyclonal (IgG) to Human Fibrinogen
Western blot, ELISA
Anti-Fibrinogen Antibody LS-C150799
Rabbit Polyclonal (IgG) to Mouse Fibrinogen
Mouse, Rat
IHC - Paraffin, IHC - Frozen, Western blot, ELISA

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Human Fibrinogen
Human, Mouse, Rat
IHC - Paraffin, IHC - Frozen, Immunofluorescence, ELISA (applications tested for the base form of this product only)


Human Fibrinogen
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein G purified


  • IHC - Paraffin (5 µg/ml)
  • IHC - Frozen
  • Immunofluorescence
  • ELISA (1:50 - 1:100)
  • (applications tested for the base form of this product only)

Specificity and Use

Fibrinogen antibody was raised against human Fibrinogen purified from plasma.
Recognizes human fibrinogen, a complex ~340kD hetero-hexameric (di-trimeric) glycoprotein consisting of 3 pairs of alpha, beta and gamma chains linked by a series of 29 disulphide bonds. The six chains are arranged in such a way that all the N-Terminal ends adjoin to form a central with two trimeric coiled coil structures connecting to outer D domains. Fibrinogen plays an important role in the coagulation process with the D and E domains interacting via the C-Terminal ends of the alpha chains during fibrin clot cross-linking. Shows minimal cross-reactivity with related serum proteins. Fibrinogen has been identified as a ferritin binding protein in the horse. Has been successfully as a capture reagent for ferritin - anti ferritin IgG complexes in horse plasma to evaluate the antibody response to ferritin by ELISA.
Immunohistochemistry: LS-B2573 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2573 was determined to be 5 ug/ml.


PBS, pH 7.4, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.
For research use only.

About Fibrinogen

Fibrinogen (factor I) is a glycoprotein in vertebrates that helps in the formation of blood clots. It consists of a linear array of three nodules held together by a very thin thread which is estimated to have a diameter between 8 and 15 Angstrom (Å). The two end nodules are alike but the center one is slightly smaller. Measurements of shadow lengths indicate that nodule diameters are in the range 50 to 70 Angstrom. The length of the dried molecule is 475 ± 25 Angstrom.


Anti-Fibrinogen antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2573 concentration 5 ug/ml. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/24/2016

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