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Anti-FGFR2 / FGF Receptor 2 Antibody (aa292-341) LS-C135703

Catalog	Size	Price
LS-C135703-50	50 µg	Unavailable

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Antibody:	Rabbit Polyclonal to Human FGFR2 / FGF Receptor 2
Reactivity:	Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep
Application:	Western blot (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Human FGFR2 / FGF Receptor 2
Host:	Rabbit
Reactivity:	Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Predicted:	Chicken, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot (0.2 - 1 µg/ml)
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:

FGFR2 / FGF Receptor 2 antibody was raised against synthetic peptide located between aa292-341 of human FGFR2 (P21802, NP_075259). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Sheep, Elephant, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig, Zebra finch (100%); Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus (92%); Zebrafish (90%).

Blocking Peptide:

LS-E21992 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C135703. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

aa292-341

Specificity:

Human FGFR2

Usage:

Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Presentation:	Lyophilized from PBS with 2% sucrose
Reconstitution:	Distilled water
Storage:	Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About FGFR2 / FGF Receptor 2

Uniprot: P21802 NCBI: NM_000141 NP_000132.3

Synonyms: FGFR2 Antibody, BEK Antibody, BBDS Antibody, Bacteria-expressed kinase Antibody, CD332 antigen Antibody, CFD1 Antibody, Craniofacial dysostosis 1 Antibody, CEK3 Antibody, Fgf bek Antibody, FGF receptor Antibody, Hydroxyaryl-protein kinase Antibody, Jackson-Weiss syndrome Antibody, JWS Antibody, FGF Receptor 2 Antibody, KSAM Antibody, KGFR Antibody, Soluble FGFR4 variant 4 Antibody, BFR-1 Antibody, TK14 Antibody, TK25 Antibody, CD332 Antibody, ECT1 Antibody, K-SAM Antibody

Description: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development.

(More About FGFR2 / FGF Receptor 2)

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Western blot

FGFR2 antibody LS-C135703 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 6/23/2017

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