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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FGFR / FGF Receptor Antibody (Extracellular Domain) LS‑C23659 Best Seller
FGF Receptor antibody LS-C23659 is an unconjugated mouse monoclonal antibody to human FGF Receptor (FGFR). Validated for WB.
Antibody
Catalog
Size
Price
LS-C23659-50
50 µg (0.5 mg/ml)
Unavailable
LS-C23659-250
250 µg (0.5 mg/ml)
Unavailable

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Product Description

FGF Receptor antibody LS-C23659 is an unconjugated mouse monoclonal antibody to human FGF Receptor (FGFR). Validated for WB.
About FGFR / FGF Receptor
Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues.

Specifications

Target
Human FGFR / FGF Receptor
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1:100 - 1:1000)
Immunogen
Purified human recombinant FGF receptor (flg-5) extracellular domain.
Epitope
Extracellular Domain
Specificity
Recognizes the extracellular domain of recombinant human FGF receptor by Western blot analysis using a 1:100 dilution together with the alkaline phosphatase detection system. Recognizes FGFR1 and FGFR2.
Usage
Suitable for use in Western Blot. Western Blot: 1:100-1:1000.
Presentation
0.1 M Tris HCl, pH 7.5.
Storage
Store product at 4°C if to be used within 2 weeks. For long-term storage, aliquot and store at 4°C. Aliquots are stable for 1 year after receipt.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/19/2018

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