Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Goat Polyclonal to Human FGF23
Western blot, ELISA
Human, Monkey (tested or 100% immunogen sequence identity)
Horse (at least 90% immunogen sequence identity)
Western blot (1:32000) & (0.5 - 1.5 µg/ml)
IHC - Paraffin
Specificity and Use
FGF23 antibody was raised against synthetic peptide C-RHTRSAEDDSERD from an internal region of human FGF23 (NP_065689.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant (100%); Horse (92%); Mouse, Rat, Panda (85%).
LS-E26241 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54835. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
FGF23 is a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR).