Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey (tested or 100% immunogen sequence identity)
Horse (at least 90% immunogen sequence identity)
Western blot (1:32000) & (0.5 - 1.5 µg/ml)
IHC - Paraffin
Specificity and Use
FGF23 antibody was raised against synthetic peptide C-RHTRSAEDDSERD from an internal region of human FGF23 (NP_065689.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant (100%); Horse (92%); Mouse, Rat, Panda (85%).
LS-E26241 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54835. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
FGF23 is a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR).