FGD4

FYVE, RhoGEF and PH domain containing 4

FGD4 is a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

☰ Filters

Products

Antibodies (10)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (10)

Recombinant (1)

Target

FGD4 (13)

Reactivity

Human (10)

Mouse (1)

Rat (1)

Application

IHC (1)

IHC-P (1)

WB (10)

ELISA (6)

ICC (1)

Host

rabbit (10)

Isotype

IgG (8)

Clonality

polyclonal pc (10)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (5)

Epitope

aa157-186 (7)

aa49-327 (1)

Publications

No (13)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

Select

FGD4 Antibody (aa49-327) LS-C186104

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa49-327) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

FGD4 Antibody (aa157-186) LS-C321361

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa157-186) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

FGD4 Antibody (aa157-186, Biotin) LS-C257213

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa157-186) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

FGD4 Antibody (aa157-186, FITC) LS-C257214

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa157-186) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

FGD4 Antibody (aa157-186, APC) LS-C257212

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa157-186) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

FGD4 Antibody (aa157-186, PE) LS-C257216

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa157-186) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

FGD4 Antibody (aa157-186, Azide-free, HRP) LS-C257215

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa157-186) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

FGD4 Antibody (aa157-186) LS-C166126

Antibody:

FGD4 Rabbit anti-Human Polyclonal (aa157-186) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

FGD4 Antibody LS-C668975

Antibody:

FGD4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

FGD4 Antibody LS-C410131

Antibody:

FGD4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

Human FGD4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G73371

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.4 kDa

Price:

20 µg/$1,107

Select

Human FGD4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G95068

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.4 kDa

Price:

20 µg/$215

Select

FGD4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102268

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.4 kDa

Price:

100 µg/$710

Viewing 1-13 of 13 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.