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Anti-FERMT1 / Kindlin Antibody (aa643-660) IHC-plus™ LS-B2876

Note: This antibody replaces LS-C18416, LS-C93275, LS-C76699, LS-C40733

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular FERMT1 / Kindlin Antibodies

Anti-FERMT1 / Kindlin Antibody (aa643-660) IHC-plus™ LS-B2876
Rabbit Polyclonal (IgG) to Human FERMT1 / Kindlin
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-FERMT1 / Kindlin Antibody (aa268-297) IHC-plus™ LS-B9898
Rabbit Polyclonal to Human FERMT1 / Kindlin
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-FERMT1 / Kindlin Antibody (AP) LS-C226632
Rabbit Polyclonal (IgG) to Human FERMT1 / Kindlin
Human
Western blot, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human FERMT1 / Kindlin
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Unconjugated

Details

Human FERMT1 / Kindlin
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:1000)

Specificity and Use

FERMT1 / Kindlin antibody was raised against residues 643-660 (VHEYIGGYIFLSTRSKDQ) of the 77kD human URP1 protein. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Rabbit, Pig, Opossum, Xenopus, Zebrafish (100%); Platypus, Lizard, Stickleback, Pufferfish (94%); Gibbon, Bat, Chicken, Beetle, Tick (89%); Turkey, Nematode (83%).
aa643-660
Reacts with residues 643-660 (VHEYIGGYIFLSTRSKDQ) of the 77kD human URP1 protein. Sequence is 100% conserved between almost all species (mouse, rat, canine, bovine, chimpanzee, Xenopus).
Immunohistochemistry: LS-B2876 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2876 was determined to be 5 ug/ml.

Packaging

PBS, pH 7.2, 0.02% sodium azide.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About FERMT1 / Kindlin

Q9BQL6 NM_017671 NP_060141.3

FERMT1 Antibody, C20orf42 Antibody, DTGCU2 Antibody, Fermitin family homolog 1 Antibody, Kindlin syndrome protein Antibody, KIND1 Antibody, Kindlin 1 Antibody, UNC112A Antibody, URP1 Antibody, UNC112 related protein 1 Antibody, Fermitin family member 1 Antibody, Kindlerin Antibody, Kindlin Antibody, Kindlin-1 Antibody, Unc-112-related protein 1 Antibody

Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

Immunohistochemistry

Immunohistochemistry
Anti-FERMT1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2876 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/6/2016

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