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Anti-FCMR / FAIM3 Antibody (C-Terminus) IHC-plus™ LS-B1353

Note: This antibody replaces LS-C19447, LS-C56797, LS-C42497, LS-C132580

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular FCMR / FAIM3 Antibodies

Anti-FCMR / FAIM3 Antibody (C-Terminus) IHC-plus™ LS-B1353
Rabbit Polyclonal to Human FCMR / FAIM3
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-FCMR / FAIM3 Antibody LS-C335653
Rabbit Polyclonal (IgG) to Human FCMR / FAIM3
Human
IHC, Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human FCMR / FAIM3
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human FCMR / FAIM3
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (1 µg/ml)

Specificity and Use

FCMR / FAIM3 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human Toso.
LS-E29934 - Liquid - 50 µg - $145.00
C-Terminus
13 amino acid peptide from near the carboxy terminus of human Toso
Immunohistochemistry: LS-B1353 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1353 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About FCMR / FAIM3

O60667 NM_005449 NP_005440.1

FCMR Antibody, FAIM3 Antibody, Immunoglobulin mu Fc receptor Antibody, TOSO Antibody, Fc mu receptor Antibody, IgM Fc receptor Antibody

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Immunohistochemistry

Immunohistochemistry
Anti-FAIM3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1353 concentration 5 ug/ml.

Western blot

Western blot
Western blot of Toso in human lung tissue lysate with Toso antibody at 1 ug/ml in either the (A) presence, or (B) absence of blocking peptide.

Requested From: United States
Date Requested: 12/10/2016

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