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| Catalog Number | Size | Price |
|---|---|---|
| LS-C500683-50 | 50 µg | $294 |
| LS-C500683-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human FCHO2 Antibody (IF, WB) LS‑C500683
Polyclonal Rabbit anti‑Human FCHO2 Antibody (IF, WB) LS‑C500683
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
FCHO2 antibody LS-C500683 is an unconjugated rabbit polyclonal antibody to FCHO2 from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
Target
Human FCHO2
Synonyms
FCHO2 | FCH domain only 2 | FCH domain only protein 2
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human F-BAR domain only protein 2 protein (100-203AA)
Specificity
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
Applications
- Immunofluorescence
- Western blot
- ELISA
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
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Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
Western blot, Immunoprecipitation
Source:
E. coli
Tag:
His
Reactivity:
Mouse
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
