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Anti-FCGR2 / CD32 Antibody (clone AT10, Low Endotoxin) LS-C187457

Ordering

Wt. Vol. Conc. Price
500 µg - 1 mg/ml $445
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular FCGR2 / CD32 Antibodies

Anti-FCGR2 / CD32 Antibody (clone 6C4 (CD32), APC) LS-C107278
Mouse Monoclonal [clone 6C4 (CD32)] (IgG1,k) to Human FCGR2 / CD32
Human
Flow Cytometry
APC Conjugated
Flow Cytometry Image
Anti-FCGR2 / CD32 Antibody (clone 16D6) LS-C114762
Mouse Monoclonal [clone 16D6] (IgG1) to Human FCGR2 / CD32
Human
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone AT10] (IgG1) to Human FCGR2 / CD32
Human, Monkey, Dog, Pig, Rhesus monkey
IHC - Frozen, Immunoprecipitation, Flow Cytometry, Functional Assay (applications tested for the base form of this product only)
Unconjugated, Low Endotoxin

Details

Human FCGR2 / CD32
Mouse
Human, Monkey, Dog, Pig, Rhesus monkey (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [AT10]
Unconjugated
Protein A purified
Low Endotoxin. Also available Unmodified.

Applications

  • IHC - Frozen (1:500 - 1:1000)
  • Immunoprecipitation (20 µg/ml)
  • Flow Cytometry
  • Functional Assay
  • (applications tested for the base form of this product only)

Specificity and Use

FCGR2 / CD32 antibody was raised against k562 cell line.
Recognizes the human CD32 antigen, a ~40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Clone AT10 blocks the binding of IgG to Fc gamma RII.
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Packaging

PBS
Store at -20°C. Minimize freezing and thawing.
For research use only.

About FCGR2 / CD32

CD32 is a surface receptor protein and part of a large population of B cell co-receptors, which act to modulate signaling. It has a low-affinity for IgG antibodies and down-regulates antibody production in the presence of IgG. This feedback loop acts to lower the production of IgG by B cells when there is a surplus in the body. Monoclonal antibodies can distinguish between CD32A and CD32B.

Requested From: United States
Date Requested: 12/4/2016

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