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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FCAR / CD89 Antibody (RPE) LS‑C43948
Note: This antibody replaces LS-C57496
Antibody
CD89 antibody LS-C43948 is an RPE-conjugated mouse monoclonal antibody to human CD89 (FCAR). Validated for ELISA, Flow, IP and WB.
Catalog
Size
Price
LS-C43948-100
100 tst
Unavailable

Popular FCAR / CD89 Products

Flow cytometry of human peripheral blood granulocytes with Mouse anti-Human CD89:Low endotoxin This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Western blot, Immunoprecipitation, Flow Cytometry, ELISA, Functional Assay
Antibody
Species: Human
Applications: Western blot
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

CD89 antibody LS-C43948 is an RPE-conjugated mouse monoclonal antibody to human CD89 (FCAR). Validated for ELISA, Flow, IP and WB.
About FCAR / CD89
FCAR / CD89 is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. P24071 NM_002000 NP_001991.1

FCAR Antibody, CD89 antigen Antibody, Fc alpha receptor Antibody, IgA Fc receptor Antibody, CD89 Antibody


Specifications

Target
Human FCAR / CD89
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
R. Phycoerythrin. Also available Unconjugated or conjugated with FITC.
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
FCAR / CD89 antibody was raised against recombinant soluble human Fc alpha R.
Specificity
Recognizes the human CD89 cell surface antigen, a 50-75kD cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R). CD89 is expressed by peripheral blood monocytes and neutrophils. MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request.
Presentation
Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Reconstitution
100 tst Distilled Water.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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