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Anti-FBXW11 Antibody (N-Terminus) LS-C60083

Ordering

Wt. Vol. Conc. Price
100 µg - - $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular FBXW11 Antibodies

Anti-FBXW11 Antibody (aa168-196, AP) LS-C222527
Rabbit Polyclonal (IgG) to Human FBXW11
Human
IHC, Western blot, Flow Cytometry, ELISA
AP Conjugated
Anti-FBXW11 Antibody (aa168-196, FITC) LS-C222530
Rabbit Polyclonal (IgG) to Human FBXW11
Human
IHC, Western blot, Flow Cytometry, ELISA
FITC Conjugated
Anti-FBXW11 Antibody (aa168-196, PE) LS-C222533
Rabbit Polyclonal (IgG) to Human FBXW11
Human
IHC, Western blot, Flow Cytometry, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human FBXW11
Human, Monkey, Mouse, Bovine, Dog, Chicken
Western blot, ELISA
Unconjugated

Details

Human FBXW11
Rabbit
Human, Monkey, Mouse, Bovine, Dog, Chicken (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1:200 - 1:1000)
  • ELISA (1:10000 - 1:100000)

Specificity and Use

FBXW11 antibody was raised against synthetic peptide corresponding to a region near the N-terminal of human RTrCP2 protein.
N-Terminus
human RTrCP2 protein. A BLAST analysis was used to suggest cross-reactivity with RTrCP2 from human, mouse, dog, bovine, chimpanzee, chicken and horse based on a 100% homology with the immunizing sequence. Cross-reactivity with RTrCP2 from other sources has not been determined
This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~58 kD in size corresponding to RTrCP2 by western blotting in the appropriate cell lysate or extract. The predicted molecular weight of RTrCP2 is 62.1 kD.

Packaging

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About FBXW11

Q9UKB1 AB033281 BAA92331.1

FBXW11 Antibody, BTRC2 Antibody, BTRCP2 Antibody, F-box protein Fbw1b Antibody, Fbw11 Antibody, FBXW1B Antibody, Hos Antibody, FBW1B Antibody, Homologous to Slimb protein Antibody, KIAA0696 Antibody

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling.

Western blot

Western blot
Anti-bTrCP2 Antibody - Western Blot. Western blot of affinity purified anti-bTrCP2 antibody shows detection of mouse and human bTrCP2 (arrowhead) in NIH3T3 (lane 1) and 293 (lane 2) whole cell lysates, respectively. The band appears as a 58 kD protein, although a 62.1 kD band is predicted. The identity of faint higher molecular weight bands is not known. The primary antibody was used at a 1:200 dilution incubated in 5% BLOTTO overnight at 4C. Detection occurred using HRP conjugated Goat-anti-Rabbit IgG (LS-C60865) diluted 1:20000 in blocking buffer (p/n MB-070) for 1 h at 4C.
 

Requested From: United States
Date Requested: 12/5/2016

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