FBXO6

F-box protein 6

Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes. Involved in endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranlocated into the cytosol and promoting their ubiquitination and subsequent degradation. Able to recognize and bind denatured glycoproteins, which are modified with not only high-mannose but also complex-type oligosaccharides. Also recognizes sulfated glycans. Also involved in DNA damage response by specifically recognizing activated CHEK1 (phosphorylated on 'Ser-345'), promoting its ubiquitination and degradation. Ubiquitination of CHEK1 is required to insure that activated CHEK1 does not accumulate as cells progress through S phase, or when replication forks encounter transient impediments during normal DNA replication.

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Products

Antibodies (31)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (31)

Recombinant (3)

Target

FBXO6 (36)

Reactivity

Human (31)

Mouse (2)

Rat (1)

Application

IHC (9)

IHC-P (3)

WB (29)

ELISA (9)

IP (1)

Peptide-ELISA (1)

Host

rabbit (11)

mouse (19)

goat (1)

Isotype

IgG (9)

IgG1 (3)

IgG1,k (6)

IgG2a (2)

IgG2b (6)

IgG3 (2)

Clonality

monoclonal mc (19)

polyclonal pc (12)

Clone

FBOX 3a9/1 (1)

OTI1H8 (2)

OTI2C1 (2)

OTI6A4 (2)

OTI7A10 (2)

OTI7A4 (2)

OTI7C2 (2)

Format

APC Conjugated (2)

Biotin Conjugated (2)

Carrier-free (6)

FITC Conjugated (2)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (20)

Epitope

aa280-293 (1)

Publications

No (36)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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FBXO6 Antibody LS-C153065

Antibody:

FBXO6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$489

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FBXO6 Antibody LS-C675745

Antibody:

FBXO6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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FBXO6 Antibody LS-C665550

Antibody:

FBXO6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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FBXO6 Antibody (clone OTI7A4) LS-C795405

Antibody:

FBXO6 Mouse anti-Human Monoclonal (OTI7A4) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FBXO6 Antibody (clone OTI7A4, Carrier-free) LS-C792432

Antibody:

FBXO6 Mouse anti-Human Monoclonal (Carrier-free) (OTI7A4) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

FBXO6 Antibody (clone OTI7A10) LS-C795417

Antibody:

FBXO6 Mouse anti-Human Monoclonal (OTI7A10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FBXO6 Antibody (clone OTI7A10, Carrier-free) LS-C792440

Antibody:

FBXO6 Mouse anti-Human Monoclonal (Carrier-free) (OTI7A10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

FBXO6 Antibody LS-C675746

Antibody:

FBXO6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

FBXO6 Antibody (clone OTI7C2) LS-C795416

Antibody:

FBXO6 Mouse anti-Human Monoclonal (OTI7C2) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FBXO6 Antibody (clone OTI7C2, Carrier-free) LS-C792444

Antibody:

FBXO6 Mouse anti-Human Monoclonal (Carrier-free) (OTI7C2) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

FBXO6 Antibody LS-C307983

Antibody:

FBXO6 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

FBXO6 Antibody (HRP) LS-C542118

Antibody:

FBXO6 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

FBXO6 Antibody (Biotin) LS-C521986

Antibody:

FBXO6 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

FBXO6 Antibody (FITC) LS-C532032

Antibody:

FBXO6 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

FBXO6 Antibody (APC) LS-C513772

Antibody:

FBXO6 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

FBXO6 Antibody (PE) LS-C650233

Antibody:

FBXO6 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

FBXO6 Antibody (clone FBOX 3a9/1, HRP) LS-C827957

Antibody:

FBXO6 Mouse anti-Human Monoclonal (HRP) (FBOX 3a9/1) Antibody

Reactivity:

Mouse, Human

Applications:

IHC-P, IP, WB

Format:

HRP Conjugated

Price:

0.05 mg/$634

Select

FBXO6 Antibody (clone OTI2C1) LS-C795404

Antibody:

FBXO6 Mouse anti-Human Monoclonal (OTI2C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FBXO6 Antibody (clone OTI2C1, Carrier-free) LS-C792433

Antibody:

FBXO6 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

FBXO6 Antibody (clone OTI1H8) LS-C795420

Antibody:

FBXO6 Mouse anti-Human Monoclonal (OTI1H8) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FBXO6 Antibody (clone OTI1H8, Carrier-free) LS-C792445

Antibody:

FBXO6 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H8) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

FBXO6 Antibody (clone OTI6A4) LS-C795423

Antibody:

FBXO6 Mouse anti-Human Monoclonal (OTI6A4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

FBXO6 Antibody (clone OTI6A4, Carrier-free) LS-C798782

Antibody:

FBXO6 Mouse anti-Human Monoclonal (Carrier-free) (OTI6A4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

FBXO6 Antibody LS-C310342

Antibody:

FBXO6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

FBXO6 Antibody LS-C486334

Antibody:

FBXO6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$412

Viewing 1-25 of 36 product results

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