Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
FBL / FIB / Fibrillarin
fibrillarin
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239).
| Gene Name: | fibrillarin |
| Synonyms: | FBL, FLRN, FBRL, FIB1, Fibrillarin, RNU3IP1, FIB |
| Target Sequences: | NM_001436 NP_001427.2 P22087 |
Publications (3)
1
Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse. Beyret E, Lin H. Developmental biology. 2011 355:215-26. (IHC-Fr; Mouse)
[PubMed:21539824]
[PMC:PMC3443393]
2
The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability. Jean-Clément Mars, Michel G Tremblay, Mélissa Valere, Dany S Sibai, Marianne Sabourin-Felix, Frédéric Lessard, Tom Moss. NAR cancer. 2020 December;2:zcaa032. [Full Text Article]
[PubMed:33196044]
[PMC:PMC7646227]
Related Antibodies: LS-C155047.
3
Ribosomal DNA promoter recognition is determined in vivo by cooperation between UBTF1 and SL1 and is compromised in the UBTF-E210K neuroregression syndrome. Michel G Tremblay, Dany S Sibai, Melissa Valère, Jean-Clément Mars, Frédéric Lessard, Roderick T Hori, Mohammad Moshahid Khan, Victor Y Stefanovsky, Mark S LeDoux, Tom Moss. PLoS genetics. 2022 February;18:e1009644. [Full Text Article]
[PubMed:35139074]
[PMC:PMC8863233]
Related Antibodies: LS-C155047.
☰ Filters
Products
Antibodies
(39)
ELISA Kits
(8)
Proteins
(8)
Type
Over-Expression Lysate
(2)
Primary
(39)
Recombinant
(6)
Sandwich
(8)
Target
FBL / FIB / Fibrillarin
(55)
Reactivity
Human
(40)
Mouse
(13)
Rat
(20)
Bovine
(5)
Chicken
(1)
Chimpanzee
(3)
Dog
(5)
Guinea pig
(5)
Hamster
(2)
Horse
(5)
Mammal
(1)
Monkey
(8)
Porcine
(1)
Rabbit
(2)
Sheep
(1)
Xenopus
(1)
Yeast
(1)
Zebrafish
(1)
Application
IHC
(12)
IHC-P
(7)
WB
(38)
DB
(2)
ELISA
(2)
ICC
(4)
IF
(9)
IP
(8)
Peptide-ELISA
(3)
Host
rabbit
(30)
mouse
(7)
goat
(2)
Product Group
IHCPlus
(3)
Isotype
IgG
(11)
IgG1
(6)
IgG2a,k
(1)
Clonality
monoclonal mc
(7)
polyclonal pc
(32)
Clone
2350C1
(2)
28F2
(1)
38F3
(1)
4G9-E4
(1)
Format
96-Well Microplate
(1)
96-Well Strip Plate
(7)
APC
(2)
APC Conjugated
(2)
Biotin Conjugated
(3)
Cy3 Conjugated
(2)
Cy7 Conjugated
(2)
FITC Conjugated
(3)
HRP Conjugated
(3)
PE Conjugated
(2)
Preservative Free
(1)
Unconjugated
(22)
Epitope
aa61-110
(4)
aa1-50
(1)
aa105-135
(1)
aa121-135
(1)
aa271-321
(1)
aa99-110
(1)
Publications
No
(54)
Yes
(1)
Sample Type
Plasma
(3)
Serum
(3)
Tissue Homogenates
(1)
Tag
6His-SUMO, N-terminus
(1)
GST
(1)
His
(1)
His-T7, N-terminus
(2)
Myc-DDK (Flag)
(3)
Species
Arabidopsis thaliana
(1)
Human
(5)
Rat
(1)
Source
293T Cells
(1)
E. coli
(4)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(3)
E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
FBL / FIB / Fibrillarin Goat anti-Human Polyclonal (aa99-110) Antibody
Xenopus, Zebrafish, Horse, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
FBL / FIB / Fibrillarin Mouse anti-Yeast Monoclonal (38F3) Antibody
Rat, Human
ICC, IF, WB
Unconjugated
500 µl/$376
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (aa61-110) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (aa61-110) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (aa61-110) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (aa61-110) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (aa271-321) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
FBL / FIB / Fibrillarin Goat anti-Human Polyclonal (aa121-135) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (aa105-135) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, IP, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IP, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IP, WB
Unconjugated, Preservative Free
100 µl/$412
E. coli
His-T7, N-terminus
28.7kDa
10 µg/$267; 50 µg/$352; 200 µg/$705; 100 µg/$565; 1 mg/$1,728; 500 µg/$1,303; 5 mg/$2,680; 2 mg/$1,906
![FBL / FIB / Fibrillarin Antibody - Immunofluorescence of monoclonal antibody to FBL on HeLa cell . [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/fbl-fib-fibrillarin-antibody-clone-4g9-e4-ls-c197156/144761_5094808.jpg)
FBL / FIB / Fibrillarin Mouse anti-Human Monoclonal (4G9-E4) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
FBL / FIB / Fibrillarin Mouse anti-Human Monoclonal Antibody
Rat, Mammal, Human
IF, WB
Unconjugated
100 µl/$436
FBL / FIB / Fibrillarin Mouse anti-Yeast Monoclonal (28F2) Antibody
Yeast
IF, IP, WB
Unconjugated
500 µl/$376
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FBL / FIB / Fibrillarin Rabbit anti-Rat Polyclonal Antibody
Rat, Human
ICC, IP, WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
FBL / FIB / Fibrillarin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
FBL / FIB / Fibrillarin Mouse anti-Human Monoclonal (2350C1) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
FBL / FIB / Fibrillarin Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µg/$786
Viewing 1-25
of 55
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
