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FASN / Fatty Acid Synthase
fatty acid synthase
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
| Gene Name: | fatty acid synthase |
| Synonyms: | FASN, Fatty acid synthase, OA-519, SDR27X1 |
| Target Sequences: | NM_004104 NP_004095.4 P49327 |
Publications (8)
1
FAS inhibitor cerulenin reduces food intake and melanocortin receptor gene expression without modulating the other (an)orexigenic neuropeptides in chickens. Dridi S, Ververken C, Hillgartner FB, Arckens L, Lutgarde A, Van der Gucht E, Cnops L, Decuypere E, Buyse J. American journal of physiology. Regulatory, integrative and comparative physiology. 2006 291:R138-47.
[PubMed:16455759]
2
Androgen deprivation increases p300 expression in prostate cancer cells. Heemers HV, Sebo TJ, Debes JD, Regan KM, Raclaw KA, Murphy LM, Hobisch A, Culig Z, Tindall DJ. Cancer research. 2007 67:3422-30.
[PubMed:17409453]
3
1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer. Vvere AL, Kridel SJ, Wheeler FB, Lewis JS. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008 49:327-34.
[PubMed:18199615]
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FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (aa942-973) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
FASN / Fatty Acid Synthase Goat anti-Human Polyclonal (aa2118-2129) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
FASN / Fatty Acid Synthase Mouse anti-Human Monoclonal (3F2-1F3) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$423
Sandwich
96-Well Microplate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FASN / Fatty Acid Synthase Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Chicken, Rat, Mouse, Pig, Primate, Human
IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$460
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (aa1175-1225) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (aa2462-2511) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, IP, WB
Unconjugated
20 µl/$299; 50 µl/$341; 100 µl/$427; 200 µl/$539
Cancer
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC-P, IP, WB
Unconjugated
50 µl/$460
E. coli
His
28.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
E. coli
6His, N-terminus
41.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
FASN / Fatty Acid Synthase Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
IF, IP, WB
Unconjugated
100 µl/$391
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (aa7-287) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (aa401-694) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P
Unconjugated
100 µl/$412
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (aa2155-2495) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
293T Cells
Myc-DDK (Flag)
273.2 kDa
20 µg/$215
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
FASN / Fatty Acid Synthase Rabbit anti-Human Polyclonal (aa1-226) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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