Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Monkey FASLG / Fas Ligand
Rabbit Polyclonal to Human FASLG / Fas Ligand
Human, Mouse, Rat
Human FASLG / Fas Ligand
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Specificity and Use
A synthetic peptide derived from C-terminus of human Fas Ligand.
Fas ligand is a cell surface molecule belonging to the tumor necrosis factor family, binds to its receptor Fas, thus inducing apoptosis. Various cells express Fas, where Fas ligand is expressed predominantly on activated T cells. Fas and Fas ligand are involved in the down-regulation of immune reactions as well as T cell-mediated cytotoxicity. cross reacts with mouse and rat.
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.