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Anti-FAP-1 / PTPN13 Antibody (aa1279-1883) LS-C148268

Ordering

Wt. Vol. Conc. Price
- 50 µl - $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Related Products

Most Popular FAP-1 / PTPN13 Antibodies

Anti-FAP-1 / PTPN13 Antibody (aa1279-1883) LS-C148268
Rabbit Polyclonal to Human FAP-1 / PTPN13
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-FAP-1 / PTPN13 Antibody (aa1760-1775) LS-C148269
Rabbit Polyclonal to Human FAP-1 / PTPN13
Human, Monkey
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human FAP-1 / PTPN13
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Human FAP-1 / PTPN13
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)

Specificity and Use

FAP-1 / PTPN13 antibody was raised against recombinant protein corresponding to aa 1279-1883 of human FAP-1 protein, GenBank no. NP_542414.1. This peptide sequence is conserved in multiple isoforms of FAP-1. These FAP-1 isoforms are of varying amino acid (aa) lengths and include: (1) NP_542414.1 = 2485 aa, FAP-1 isoform 1. (2) BAD92141.1 = 2434 aa, FAP-1 isoform 2. (3) NP_542415.1 = 2294 aa, FAP-1 isoform 3. (4) NP_542416.1 = 2490 aa, FAP-1 isoform 4. (5) AAH39610.1 = 604 aa, FAP-1. (6) AAF63474.1 =499 aa, FAP-1.
aa1279-1883
FAP-1 typically migrates at ~270 kD on western blots. Thus for SDS-PAGE and western blot, the researcher should use techniques optimized for the transfer of proteins with high molecular weights. The actual molecular weight of FAP-1 observed depends on the isoform expression.

Packaging

Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About FAP-1 / PTPN13

Q12923 NM_006264 NP_006255.1

PTPN13 Antibody, FAP-1 Antibody, HPTP1E Antibody, HPTPE1 Antibody, Fas associated phosphatase 1 Antibody, Phosphatase rip Antibody, PTP-BAS Antibody, PTP-E1 Antibody, PTP-BL Antibody, PTP1E Antibody, PTPLE Antibody, PNP1 Antibody, PTPL1 Antibody

FAP-1 / PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of FAP-1 in formalin-fixed, paraffin embedded ovarian carcinoma cores from a tissue microarray using LS-C148268 at 1:2000. A-D, samples are from four different patients. A1-D1 are high magnification images from A-D, respectively. Hematoxylin-Eosin counterstain.

Immunohistochemistry

Immunohistochemistry
Immunocytochemistry of FAP-1 in cell lines using LS-C148268 at 1:2000. In ovarian carcinoma cell lines FAP-1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human 293 kidney and Jurkat T cell lines were used as positive and negative controls, respectively. The staining data correlates with the western blot data (figure to the left).

Western blot

Western blot
Western blot of FAP-1 using LS-C148268 at 1:2000. In ovarian carcinoma cell lines FAP-1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human Jurkat T and 293 kidney cell lines were used as negative and positive controls, respectively.
 

Requested From: United States
Date Requested: 12/2/2016

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