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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FAK / Focal Adhesion Kinase Antibody (phospho‑Tyr861) LS‑C117355
Note: This antibody replaces LS-C65845, LS-C65874, LS-C53787, LS-C34053, LS-C51176
Focal Adhesion Kinase antibody LS-C117355 is an unconjugated rabbit polyclonal antibody to Focal Adhesion Kinase (FAK) from human, mouse and rat. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C117355-50
50 µl
Unavailable
LS-C117355-100
100 µl
Unavailable

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Product Description

Focal Adhesion Kinase antibody LS-C117355 is an unconjugated rabbit polyclonal antibody to Focal Adhesion Kinase (FAK) from human, mouse and rat. Validated for Peptide-ELISA and WB.
About FAK / Focal Adhesion Kinase
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Q05397 NM_005607 NP_005598.3

PTK2 Antibody, FADK Antibody, Fadk1 Antibody, Focal adhesion kinase Antibody, FRNK Antibody, FADK 1 Antibody, Focal adhesion kinase 1 Antibody, FAK1 Antibody, p125FAK Antibody, PPP1R71 Antibody, Protein-tyrosine kinase 2 Antibody, PTK2 protein tyrosine kinase 2 Antibody, FAK Antibody, pp125 FA kinase Antibody, Pp125FAK Antibody


Specifications

Target
Human FAK / Focal Adhesion Kinase
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
Immunogen
Synthetic peptide from human FAK around the phosphorylation site of Tyr861.
Epitope
pTyr861
Specificity
FAK (Phospho-Tyr861) Antibody detects endogenous levels of FAK only when phosphorylated at tyrosine861.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/19/2018

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