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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FAK / Focal Adhesion Kinase Antibody (aa1‑423, Agarose) LS‑C15114
Antibody
Focal Adhesion Kinase antibody LS-C15114 is an Agarose-conjugated mouse monoclonal antibody to human Focal Adhesion Kinase (FAK). Validated for IP and WB.
Catalog
Size
Price
LS-C15114-200
200 µg
Unavailable

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Product Description

Focal Adhesion Kinase antibody LS-C15114 is an Agarose-conjugated mouse monoclonal antibody to human Focal Adhesion Kinase (FAK). Validated for IP and WB.
About FAK / Focal Adhesion Kinase
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Q05397 NM_005607 NP_005598.3

PTK2 Antibody, FADK Antibody, Fadk1 Antibody, Focal adhesion kinase Antibody, FRNK Antibody, FADK 1 Antibody, Focal adhesion kinase 1 Antibody, FAK1 Antibody, p125FAK Antibody, PPP1R71 Antibody, Protein-tyrosine kinase 2 Antibody, PTK2 protein tyrosine kinase 2 Antibody, FAK Antibody, pp125 FA kinase Antibody, Pp125FAK Antibody


Specifications

Target
Human FAK / Focal Adhesion Kinase
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Agarose
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
Immunogen
GST fusion protein corresponding to residues 1-423 of human FAK.
Epitope
aa1-423
Specificity
Recognizes FAK (Focal Adhesion Associated Protein Tyrosine Kinase, BC3).
Usage
Suitable for immunoprecipitation and affinity purification. Immunoprecipitation: 5-10 ug (10-20ul) of this lot of antibody-agarose immunoprecipitated FAK from a mouse 3T3/A31 RIPA cell lysate, as confirmed by subsequent immunoblot analysis using anti-FAK.
Presentation
Covalently linked to 200 ml of protein G agarose beads, provided as a 50% gel slurry suspended in PBS, 0.05% sodium azide for a total volume of 400ml. Liquid suspension.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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