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Anti-FAK / Focal Adhesion Kinase Antibody (aa1-423, Agarose) LS-C15114

Catalog	Size	Price
LS-C15114-200	200 µg	Unavailable

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Antibody:	Mouse Monoclonal (IgG1) to Human FAK / Focal Adhesion Kinase
Reactivity:	Human
Application:	Western blot, Immunoprecipitation
Format:	Agarose Conjugated

Details

Target:	Human FAK / Focal Adhesion Kinase
Host:	Mouse
Reactivity:	Human (tested or 100% immunogen sequence identity)
Clonality:	IgG1 Monoclonal
Conjugations:	Agarose
Purification:	Purified
Modifications:	Unmodified

Applications

Approved:

Western blot
Immunoprecipitation

Specificity and Use

Immunogen:	GST fusion protein corresponding to residues 1-423 of human FAK.
Epitope:	aa1-423
Specificity:	Recognizes FAK (Focal Adhesion Associated Protein Tyrosine Kinase, BC3).
Usage:	Suitable for immunoprecipitation and affinity purification. Immunoprecipitation: 5-10 ug (10-20ul) of this lot of antibody-agarose immunoprecipitated FAK from a mouse 3T3/A31 RIPA cell lysate, as confirmed by subsequent immunoblot analysis using anti-FAK.

Packaging

Presentation:	Covalently linked to 200 ml of protein G agarose beads, provided as a 50% gel slurry suspended in PBS, 0.05% sodium azide for a total volume of 400ml. Liquid suspension.
Storage:	Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About FAK / Focal Adhesion Kinase

Uniprot: Q05397 NCBI: NM_005607 NP_005598.3

Synonyms: PTK2 Antibody, FADK Antibody, Fadk1 Antibody, Focal adhesion kinase Antibody, FRNK Antibody, FADK 1 Antibody, Focal adhesion kinase 1 Antibody, FAK1 Antibody, p125FAK Antibody, PPP1R71 Antibody, Protein-tyrosine kinase 2 Antibody, PTK2 protein tyrosine kinase 2 Antibody, FAK Antibody, pp125 FA kinase Antibody, Pp125FAK Antibody

Description: Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development.

(More About FAK / Focal Adhesion Kinase)

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