F8 / FVIII / Factor VIII

coagulation factor VIII, procoagulant component

F8 / FVIII / Factor VIII is coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

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Antibodies (120)

ELISA Kits (21)

Proteins (9)

Type

Competitive EIA (1)

Custom (1)

Primary (120)

Recombinant (9)

Sandwich (16)

Sandwich CLIA (3)

Target

F8 / FVIII / Factor VIII (150)

Reactivity

Human (108)

Mouse (20)

Rat (2)

Bovine (3)

Chicken (1)

Dog (13)

Monkey (5)

Pig (9)

Rabbit (4)

Sheep (4)

Application

IHC (7)

IHC-P (4)

WB (81)

ELISA (58)

IE (2)

IF (2)

IP (1)

Peptide-ELISA (2)

RIA (2)

Host

rabbit (68)

mouse (40)

rat (1)

sheep (11)

Product Group

IHCPlus (2)

PathPlus Cancer (1)

Isotype

IgG (28)

IgG1 (18)

IgG1,k (5)

IgG2a (16)

IgG2b,k (1)

Clonality

monoclonal mc (44)

polyclonal pc (76)

Clone

10101 (1)

14E8-F7 (1)

15D9-F9A11 (1)

1C2-G10F10 (1)

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226 (1)

402 (1)

5E9B2 (2)

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F8 2.2.9 (1)

F8 5.5.72 (1)

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F8C 27.4 (2A5) (1)

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12 x 8-Well Microstrips (2)

96-Well Microplate (3)

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Epitope

aa1669-1824 (8)

aa1854-1989 (8)

aa1887-2044 (8)

aa2191-2337 (8)

aa2253-2346 (8)

aa1790-1839 (4)

2130-2210 aa, C-terminal (1)

C-Terminus (1)

Ser2194 (1)

aa1264-1278 (1)

aa2161-2210 (1)

aa2187-2209 (1)

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Publications

No (149)

Yes (1)

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Cell Culture Supernatants (1)

Cell Supernatant (1)

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Serum (11)

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GST (1)

GST, N-terminus (1)

His (3)

His, C-Terminal (1)

His, N-Terminal (3)

Species

Dog (1)

Human (6)

Mouse (1)

Pig (1)

Source

E. coli (7)

Wheat Germ Extract (2)

Purification

Purified (3)

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PathPlus™ F8 / FVIII / Factor VIII Antibody (clone F8 2.2.9) LS-B3124

Cancer

(5.0) Rating

Antibody:

F8 / FVIII / Factor VIII Mouse anti-Human Monoclonal (F8 2.2.9) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$495

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F8 / FVIII / Factor VIII Antibody (aa1669-1824) LS-B11726

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Pig Polyclonal (aa1669-1824) Antibody

Reactivity:

Pig

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$460

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IHC-plus™ F8 / FVIII / Factor VIII Antibody LS-B2979

(4.0) Rating

Antibody:

F8 / FVIII / Factor VIII Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

0.5 mg/$440

Select

F8 / FVIII / Factor VIII Antibody LS-C414216

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$432

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F8 / FVIII / Factor VIII Antibody (HRP) LS-C86644

Antibody:

F8 / FVIII / Factor VIII Sheep anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IE

Format:

HRP Conjugated

Price:

200 µg/$765

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F8 / FVIII / Factor VIII Antibody (HRP) LS-C23380

Antibody:

F8 / FVIII / Factor VIII Sheep anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IE

Format:

HRP Conjugated

Price:

200 µg/$657

Select

F8 / FVIII / Factor VIII Antibody (aa1790-1839) LS-C135701

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Human Polyclonal (aa1790-1839) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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F8 / FVIII / Factor VIII Antibody (Ser2194) LS-C176016

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Human Polyclonal (Ser2194) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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F8 / FVIII / Factor VIII Antibody (Biotin) LS-C193840

Antibody:

F8 / FVIII / Factor VIII Sheep anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

100 µg/$850

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F8 / FVIII / Factor VIII Antibody (aa1669-1824, Biotin) LS-C300526

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Pig Polyclonal (aa1669-1824) (Biotin) Antibody

Reactivity:

Pig

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$334; 200 µl/$387; 500 µl/$563; 1 ml/$678; 2 ml/$915; 5 ml/$1,541

Select

F8 / FVIII / Factor VIII Antibody (aa2187-2209) LS-C800279

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Human Polyclonal (aa2187-2209) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

Monkey F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F42450

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$745

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Human F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F13177

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

Select

Mouse F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F22226

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Monkey F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F32124

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

2.344 - 150 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$579

Select

Human F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F10415

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.0018 - 0.92 IU/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$896

Select

Human F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F5055

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$798

Select

Mouse F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F5831

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$818

Select

F8 / FVIII / Factor VIII Antibody (C-Terminus) LS-C352184

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Dog, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

F8 / FVIII / Factor VIII Antibody (PE) LS-C650171

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

Select

F8 / FVIII / Factor VIII Antibody LS-C485556

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

Human F8 / FVIII / Factor VIII Protein (Recombinant His, C-Terminal) (aa1887-2044) - LS-G14405

Source:

E. coli

Tag:

His, C-Terminal

Molecular Weight:

20.1 kDa

Price:

10 µg/$249; 50 µg/$307; 200 µg/$482; 1 mg/$1,325; 5 mg/$2,204; 2 mg/$1,480

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Mouse F8 / FVIII / Factor VIII Protein (Recombinant His) (aa1854-1988) - LS-G14409

Source:

E. coli

Tag:

His

Molecular Weight:

17.6 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Rat F8 / FVIII / Factor VIII (Sandwich ELISA) ELISA Kit - LS-F24196

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

F8 / FVIII / Factor VIII Antibody (aa1854-1989) LS-C293402

Antibody:

F8 / FVIII / Factor VIII Rabbit anti-Mouse Polyclonal (aa1854-1989) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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