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Anti-F3 / CD142 / Tissue factor Antibody (Extracellular Domain, clone TF9-10H10) LS-C11470

Note: This antibody replaces LS-C39704

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $315
Inquire for larger quantities

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Mouse Monoclonal [clone TF9-10H10] (IgG1) to Human F3 / CD142 / Tissue factor
Human, Primate
IHC - Frozen, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated

Details

Human F3 / CD142 / Tissue factor
Mouse
Human, Primate (tested or 100% immunogen sequence identity)
Rabbit
IgG1 Monoclonal [TF9-10H10]
Protein G purified

Applications

IHC - Frozen, Immunofluorescence, Western blot, Flow Cytometry, ELISA

Specificity and Use

F3 / CD142 / Tissue factor antibody was raised against purified apoprotein of human tissue factor.
Extracellular Domain
Recognizes human CD142, also known as Tissue Factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is critical for controlling hemostasis, thrombosis and inflammation. Recognizes an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 200 mM mannitol.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About F3 / CD142 / Tissue factor

P13726 NM_001993 NP_001984.1

F3 Antibody, CD142 Antibody, CD142 antigen Antibody, TFA Antibody, Tissue factor Antibody, Thromboplastin Antibody, Coagulation factor III Antibody

F3 / CD142 / Tissue factor is coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis.

Requested From: United States
Date Requested: 9/30/2016

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