Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone SAM11] (IgG2a) to Human F2RL1 / PAR2
IHC - Paraffin, Immunofluorescence, ELISA
Mouse Monoclonal (IgG2a) to Human F2RL1 / PAR2
Human F2RL1 / PAR2
Human (tested or 100% immunogen sequence identity)
Specificity and Use
F2RL1 / PAR2 antibody was raised against human PAR2.
Recognizes human PAR2.
Suitable for use in Flow Cytometry. Flow cytometry: Use 10 ul to label 1x10^5 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2R/PAR1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection.