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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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F2R / Thrombin Receptor / PAR1 Antibody (clone N2‑11, DY488) LS‑C180675
PAR1 antibody LS-C180675 is a DY488-conjugated mouse monoclonal antibody to PAR1 (F2R / Thrombin Receptor) from human and monkey. Validated for ELISA, ICC, IHC and WB.
Catalog
Size
Price
LS-C180675-100
100 µl (1 mg/ml)
Unavailable

Popular F2R / Thrombin Receptor / PAR1 Products

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Anti-Thrombin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3969 concentration 2.5 ug/ml.
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F2R / Thrombin Receptor antibody LS-C135497 Western blot of U937 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: IHC, IHC - Paraffin, ICC, Western blot, ELISA

Product Description

PAR1 antibody LS-C180675 is a DY488-conjugated mouse monoclonal antibody to PAR1 (F2R / Thrombin Receptor) from human and monkey. Validated for ELISA, ICC, IHC and WB.
About F2R / Thrombin Receptor / PAR1
Thrombin Receptor is a Proteinase-Activated Receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. Thrombin induced RANTES expression through a PAR-1 mediated pathway influences inflammatory cell migration to the synovium in patients with rheumatoid arthritis. P25116 NM_001992 NP_001983.2

F2R Antibody, CF2R Antibody, Coagulation factor II receptor Antibody, PAR1 Antibody, PAR-1 Antibody, Thrombin receptor Antibody, TR Antibody, HTR Antibody, Protease-activated receptor 1 Antibody


Specifications

Target
Human F2R / Thrombin Receptor / PAR1
Host
Mouse
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [N2-11]
Conjugations
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • ICC (1:50)
  • Western blot (1:1000)
  • ELISA (1:100 - 1:2000)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
The oligopeptide C-NATLDPRSFLL from human Thrombin Receptor. [Swiss-Prot# P25116].
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C in the dark.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry: Thrombin Receptor Antibody (N2-11) - IHC of Thrombin Receptor on mouse skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: Thrombin Receptor Antibody (N2-11) - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: Thrombin Receptor Antibody (N2-11) - Analysis of Thrombin Receptor expression in human testis. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/19/2018

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