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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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F2 / Prothrombin / Thrombin Antibody (Gly724) LS‑C177058
Thrombin antibody LS-C177058 is an unconjugated rabbit polyclonal antibody to Thrombin (F2 / Prothrombin) from human, mouse and rat. Validated for IF, IHC and WB.
Catalog
Size
Price
LS-C177058-100
100 µl
Unavailable

Popular F2 / Prothrombin / Thrombin Products

Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Bovine
Applications: ELISA, Immunoelectrophoresis
Antibody
Species: Human
Applications: ELISA, Immunoelectrophoresis
Anti-F2 / Thrombin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2559 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA, Inhibition

Product Description

Thrombin antibody LS-C177058 is an unconjugated rabbit polyclonal antibody to Thrombin (F2 / Prothrombin) from human, mouse and rat. Validated for IF, IHC and WB.
About F2 / Prothrombin / Thrombin
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. P00734 NM_000506 NP_000497.1

F2 Antibody, Prothrombin B-chain Antibody, Coagulation factor II Antibody, FACTOR II Antibody, Prothrombin Antibody, PT Antibody, RPRGL2 Antibody, Serine protease Antibody, THPH1 Antibody, Thrombin Antibody


Specifications

Target
Human F2 / Prothrombin / Thrombin
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide around Gly724 of human Prothrombin / Thrombin
Epitope
Gly724
Specificity
Human Prothrombin / Thrombin
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.
IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.
Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.

Immunohistochemistry

IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.
IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.
Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.

Immunohistochemistry

IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.
IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.
Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.

Immunohistochemistry

IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.
IHC of Prothrombin (G724) pAb in paraffin-embedded human liver carcinoma tissue.

Western blot

Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.
Western blot of Prothrombin (G724) pAb in extracts from NIH-3T3 cells.


Requested From: 
Date Requested: 6/25/2018

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