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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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F2 / Prothrombin / Thrombin Antibody LS‑C39616
Antibody
Thrombin antibody LS-C39616 is an unconjugated sheep polyclonal antibody to human Thrombin (F2 / Prothrombin). Validated for ELISA and IE.
Catalog
Size
Price
LS-C39616-500
500 µg
Unavailable

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Applications: Western blot, ELISA, Inhibition

Product Description

Thrombin antibody LS-C39616 is an unconjugated sheep polyclonal antibody to human Thrombin (F2 / Prothrombin). Validated for ELISA and IE.
About F2 / Prothrombin / Thrombin
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. P00734 NM_000506 NP_000497.1

F2 Antibody, Prothrombin B-chain Antibody, Coagulation factor II Antibody, FACTOR II Antibody, Prothrombin Antibody, PT Antibody, RPRGL2 Antibody, Serine protease Antibody, THPH1 Antibody, Thrombin Antibody


Specifications

Target
Human F2 / Prothrombin / Thrombin
Host
Sheep
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ELISA
  • Immunoelectrophoresis
Immunogen
Human a-Thrombin inactivated with PPACK.
Specificity
Affinity-purified IgG shows reactivity to thrombin and to prothrombin by Immunoelectrophoresis and ELISA. Species cross-reactivity: Human.
Usage
Suitable for use as an enriched source of sheep antibodies to human thrombin and thrombin-inhibitor complexes by Immunoelectrophoresis and ELISA.
Presentation
10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 50% glycerol.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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